. 2023 Apr 3;10:1095160. doi: 10.3389/fvets.2023.1095160

Table 3.

Effect of postweaning enterotoxigenic E. coli (ETEC) F18 challenge and dietary supplementation with plant combinations on red blood cell, hemoglobin, hematocrit, and platelet concentrations in organic weaner pigs.

Item^d	Treatment^e				SEM^f	P -value
	NC	PC	GA	GB		Treat	Day	Treat × day
RBC (10⁶/μL)						0.011	0.001	<0.001
Weaning	6.35	6.34	6.13	6.14	0.133
Day 3	6.20	6.29	6.03	6.14	0.192
Day 5	6.28	6.53	6.11	6.39	0.197
Day 7	6.36^a	7.29^b	6.32^a	6.27^a	0.203
Day 14	6.52	6.61	5.89	5.97	0.196
Day 21	6.86^b	6.75^b	5.51^a	5.83^a	0.197
HGB (g/L)						0.002	<0.001	<0.001
Weaning	114.02	114.15	114.86	110.11	1.982
Day 3	111.63	117.37	112.75	112.00	3.781
Day 5	113.87	118.09	114.04	113.73	2.730
Day 7	117.63^a	136.78^b	121.24^a	115.37^a	3.328
Day 14	123.98^b	124.80^b	115.10^a	112.50^a	2.701
Day 21	129.98^b	127.53^b	114.93^a	115.13^a	2.873
HCT (%)						0.029	<0.001	<0.001
Weaning	40.38^b	39.61^ab	39.92^ab	37.58^a	0.702
Day 3	37.19	38.37	37.90	37.11	1.126
Day 5	38.78	40.84	38.94	39.72	1.029
Day 7	38.85^a	44.44^b	40.11^a	38.34^a	1.132
Day 14	39.09	39.78	37.21	36.26	1.050
Day 21	42.04^b	41.62^b	37.30^a	37.10^a	1.000
MCV (fL)						0.112	<0.001	<0.001
Weaning	63.64	62.41	64.64	61.25	0.926
Day 3	60.13	60.99	62.80	60.36	0.906
Day 5	61.95	62.61	63.74	62.14	1.003
Day 7	61.32	60.88	63.66	61.11	1.144
Day 14	60.09	60.28	63.22	60.75	1.153
Day 21	61.54^a	61.49^a	68.05^b	63.91^ab	1.453
MCH (pg)						0.187	<0.001	<0.001
Weaning	17.97	18.03	18.63	17.94	0.254
Day 3	18.04	18.68	18.70	18.23	0.442
Day 5	18.19	18.00	18.69	17.80	0.253
Day 7	18.57	18.71	19.06	18.42	0.291
Day 14	19.07	18.87	19.46	18.89	0.306
Day 21	19.01^a	18.79^a	20.86^b	19.84^ab	0.360
MCHC (g/L)						0.896	<0.001	0.195
Weaning	282.58	288.09	287.21	292.50	3.701
Day 3	300.25	305.75	297.88	301.75	3.314
Day 5	293.87	289.81	292.60	285.18	3.545
Day 7	303.06	306.49	302.46	301.25	3.715
Day 14	317.06	313.52	308.26	310.87	3.506
Day 21	308.77	305.82	306.59	310.50	3.557
Reticulocytes (10⁹/L)						0.290	<0.001	<0.001
Weaning	209.53^b	182.13^ab	171.76^ab	155.85^a	13.609
Day 3	152.65^c	138.96^bc	102.60^a	112.86^ab	11.647
Day 5	182.21	153.76	115.46	119.28	18.099
Day 7	201.78	163.81	166.59	177.35	24.218
Day 14	172.99^a	159.15^a	360.49^b	227.93^c	29.300
Day 21	173.31^a	183.18^a	418.74^c	315.33^b	19.697
Platelets (10⁹/L)						0.207	0.103	0.706
Weaning	390.78	318.73	376.13	383.34	49.699
Day 3	345.21	342.52	320.39	319.34	44.776
Day 5	318.13	359.02	258.40	410.68	47.671
Day 7	277.25	312.54	343.67	398.50	49.818
Day 14	354.96	382.32	358.39	405.18	47.179
Day 21	392.00	380.10	364.25	448.62	47.830

^abc

Within a row, values that do not share a common superscript differ (P <0.05), Benjamini-Hochberg adjustment.

RBC, Red blood cell count; HGB, Hemoglobin; HCT, Hematocrit; MCV, Mean cell volume; MCH, Mean Cell Hemoglobin; MCHC, Mean red blood cell hemoglobin content.

NC, non-challenge (n = 8), standard diet; PC, challenged, standard diet (0–7 d, n = 8; 7–21 d, n = 7); GA, challenged, garlic + apple pomace (3 +3%; 0–7 d, n = 8; 7–21 d, n = 6); GB, challenged, garlic + blackcurrant (3 + 3%; n = 8).

Pooled standard error of least squared means.