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. 2023 Apr 3;14:1146798. doi: 10.3389/fendo.2023.1146798

Table 2.

Univariate and multivariate binary logistic regression analyses identifying potential factors associated with total type 2 diabetes.

Variables Unadjusted OR 95% CI p-Value Adjusted OR 95% CI p-Value
Sex: Male 1.26 1.34-1.40 <0.001 1.26 1.09-1.45 0.002
HBsAg: ≥200 0.75 0.68-0.82 <0.001 0.80 0.70-0.91 0.001
HBeAg: Positive 0.74 0.64-0.86 <0.001 0.78 0.63-0.96 0.022
HCVAb: Positive 1.42 0.99-2.03 0.057
HBV-DNA 0.002 <0.001
 ≥20000 IU/mL 1.12 1.00-1.26 0.060 1.38 1.16-1.65 <0.001
 ≥2000, <20000 IU/mL 0.81 0.69-0.94 0.006 0.88 0.72-1.08 0.221
 ≥100, <2000 IU/mL 0.99 0.88-1.12 0.921 1.08 0.93-1.26 0.323
Age (Yeas) 1.03 1.02-1.03 <0.001 1.03 1.02-1.03 <0.001
White blood cell (x109/L) 1.01 1.00-1.01 <0.001 1.01 1.00-1.01 0.049
Red blood cell (x1012/L) 0.81 0.76-0.85 <0.001 0.85 0.78-0.92 <0.001
Hemoglobin (g/L) 0.99 0.99-1.00 <0.001
Platelet (x109/L) 1.00 1.00-1.00 <0.001 1.00 1.00-1.00 <0.001
APTT (s) 0.98 0.97-0.99 <0.001 0.96 0.95-0.97 <0.001
Prothrombin Time (s) 1.02 1.01-1.03 0.007 1.21 1.05-1.39 0.008
INR 1.13 1.01-1.25 0.030 0.31 0.10-0.93 0.036
Fibrinogen (g/L) 1.09 1.05-1.13 <0.001 1.15 1.09-1.20 <0.001
Thrombin Time (s) 1.00 0.99-1.01 0.487
Total bilirubin (μmol/L) 1.00 1.00-1.00 0.151
ALT (IU/L) 1.00 1.00-1.00 0.004
AST (IU/L) 1.00 1.00-1.00 0.119
ALP (IU/L) 1.00 1.00-1.00 0.624
GGT (IU/L) 1.00 1.00-1.00 0.005
Total protein (g/L) 0.99 0.99-1.00 0.003
Albumin (g/L) 0.97 0.97-0.98 <0.001
Triglycerides (mmol/L) 1.27 1.21-1.33 <0.001 1.30 1.22-1.38 <0.001
Total Cholesterol (mmol/L) 0.94 0.91-0.98 0.004
HDL Cholesterol (mmol/L) 0.50 0.44-0.56 <0.001 0.65 0.55-0.77 <0.001
LDL Cholesterol (mmol/L) 0.93 0.88-0.98 0.005

ALP, Alkaline Phosphatase; ALT, Alanine Aminotransferase; APTT, Activated Partial Thromboplastin Time; AST, Aspartate Aminotransferase; CI, Confidence Interval; DNA, Deoxyribonucleic Acid; GGT, Gamma-glutamyl Transferase; HBeAg, Hepatitis B e Antigen; HBsAg, Hepatitis B Surface Antigen; HBV, Hepatitis B Virus; HCV, Hepatitis C Virus. HDL, High-density Lipoprotein; INR, International Normalized Ratio; LDL, Low-density Lipoprotein; OR, Odds Ratio.