Table 4.
Univariate and multivariate binary logistic regression analyses exploring potential factors associated with HbA1c ≥6.5%.
| Variables | Unadjusted OR | 95% CI | p-Value | Adjusted OR | 95% CI | p-Value |
|---|---|---|---|---|---|---|
| Sex: Male | 1.28 | 1.02-1.61 | 0.033 | – | – | – |
| HBsAg: ≥200 | 1.04 | 0.84-1.29 | 0.719 | – | – | – |
| HBeAg: Positive | 1.16 | 0.80-1.67 | 0.432 | – | – | – |
| HCVAb: Positive | 0.94 | 0.42-2.09 | 0.874 | – | – | – |
| HBV-DNA | – | – | 0.001 | – | – | 0.003 |
| ≥20000 IU/mL | 1.66 | 1.26-2.17 | <0.001 | 1.78 | 1.31-2.42 | <0.001 |
| ≥2000, <20000 IU/mL | 1.05 | 0.76-1.45 | 0.753 | 1.24 | 0.87-1.76 | 0.239 |
| ≥100, <2000 IU/mL | 0.99 | 0.76-1.28 | 0.917 | 1.17 | 0.87-1.56 | 0.300 |
| Age (Yeas) | 1.02 | 1.01-1.03 | <0.001 | 1.02 | 1.01-1.03 | <0.001 |
| White blood cell (x109/L) | 1.05 | 1.02-1.08 | 0.003 | – | – | – |
| Red blood cell (x1012/L) | 0.97 | 0.85-1.10 | 0.610 | – | – | – |
| Hemoglobin (g/L) | 1.00 | 0.99-1.00 | 0.144 | – | – | – |
| Platelet (x109/L) | 1.00 | 1.00-1.00 | 0.178 | – | – | – |
| APTT (s) | 0.99 | 0.97-1.01 | 0.206 | – | – | – |
| Prothrombin Time (s) | 1.02 | 0.99-1.05 | 0.226 | – | – | – |
| INR | 1.12 | 0.89-1.41 | 0.333 | – | – | – |
| Fibrinogen (g/L) | 1.16 | 1.08-1.26 | <0.001 | 1.13 | 1.04-1.23 | 0.003 |
| Thrombin Time (s) | 1.00 | 0.99-1.01 | 0.732 | – | – | – |
| Total bilirubin (μmol/L) | 1.00 | 1.00-1.00 | 0.318 | – | – | – |
| ALT (IU/L) | 1.00 | 1.00-1.00 | 0.022 | – | – | – |
| AST (IU/L) | 1.00 | 1.00-1.00 | 0.212 | – | – | – |
| ALP (IU/L) | 1.01 | 1.01-1.01 | <0.001 | 1.01 | 1.00-1.01 | <0.001 |
| GGT (IU/L) | 1.00 | 1.00-1.00 | <0.001 | – | – | – |
| Total protein (g/L) | 0.99 | 0.98-1.01 | 0.265 | – | – | – |
| Albumin (g/L) | 0.97 | 0.95-0.98 | <0.001 | – | – | – |
| Triglycerides (mmol/L) | 1.11 | 1.03-1.19 | 0.008 | 1.12 | 1.03-1.22 | 0.008 |
| Total Cholesterol (mmol/L) | 0.94 | 0.86-1.02 | 0.112 | – | – | – |
| HDL Cholesterol (mmol/L) | 0.47 | 0.35-0.63 | <0.001 | 0.65 | 0.47-0.88 | 0.006 |
| LDL Cholesterol (mmol/L) | 1.02 | 1.01-1.03 | <0.001 | – | – | – |
ALP, Alkaline Phosphatase; ALT, Alanine Aminotransferase; APTT, Activated Partial Thromboplastin Time; AST, Aspartate Aminotransferase; CI, Confidence Interval; DNA, Deoxyribonucleic Acid; GGT, Gamma-glutamyl Transferase; HbA1c, Glycated Hemoglobin; HBeAg, Hepatitis B e Antigen; HBsAg, Hepatitis B Surface Antigen; HBV, Hepatitis B Virus; HCV, Hepatitis C Virus. HDL, High-density Lipoprotein; INR, International Normalized Ratio; LDL, Low-density Lipoprotein; OR, Odds Ratio.