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. 2023 Apr 3;6:1123285. doi: 10.3389/frai.2023.1123285

Table 3.

Selecting effect modifiers among age, SBP, BMI, CRP, and AST.

Covariate Subgroup Optimal drug combination Effect modifier Covariate Subgroup Optimal drug combination Effect modifier
SBP Normal 123 Yes BMI Normal 123 No
High 126 Obesity 123
Age 0 - 30 126 Yes CRP Normal 12 Yes
30 - 60 123 High 123
60 - 80 12 AST Normal 123 No
High 123

The combinatorial treatment with the lowest observed failure rate varies across different patient subgroups stratified by the effect modifier.