Table 3.
Selecting effect modifiers among age, SBP, BMI, CRP, and AST.
Covariate | Subgroup | Optimal drug combination | Effect modifier | Covariate | Subgroup | Optimal drug combination | Effect modifier |
---|---|---|---|---|---|---|---|
SBP | Normal | 123 | Yes | BMI | Normal | 123 | No |
High | 126 | Obesity | 123 | ||||
Age | 0 - 30 | 126 | Yes | CRP | Normal | 12 | Yes |
30 - 60 | 123 | High | 123 | ||||
60 - 80 | 12 | AST | Normal | 123 | No | ||
High | 123 |
The combinatorial treatment with the lowest observed failure rate varies across different patient subgroups stratified by the effect modifier.