Table 3.

Codes describing the disadvantages of the UAR and strategies for improvement.

Disadvantages of the UAR	Strategies to improve the UAR
• Co-medications Not Apparent [C81] • In utero Exposure Not Apparent [C83] • Metabolites Not Apparent [C86] • Multiple Administrations to Mother Not Apparent [C87] • Prematurity Not Apparent [C93]	• Separate by Specific Cases and Scenarios [C108]
• Potential to Appear Subjective or Misinterpreted [C92]	• Explain More About How the Model was Made (Inputs and Assessments) [C97] • Explain More About UAR Advantages [C98]
• Difficult to Understand or Too Complex [C82]	• Provide Guidance to Interpret the UAR [C106] • Make Visual Representation Essential [C102] • User Friendly for Non-pharmacists [C100] • User Friendly for Pharmacists [C101] • Provide a Definitive Bottom Line [C104]
• Lack of Maternal Perspective [C84]	• Provide a Greater Maternal Emphasis [C105]
• Limited Information on Adverse Effects (Exposure-Response Relationship) [C85]	• Provide Prospective Predictive Evidence [C107]
• Not Enough for Clinical Decision-making [C88]	• Combine the UAR with Another Resource [C96]
• Unusable in Current Form (Too Novel) [C94]	• Add a Summary Statement [C95] • Give Specific Training [C99] • Overcome Simulation Skepticism [C103]