Table 1.
Baseline characteristics of patients with dementia (after propensity-matching).
| Baseline characteristics | Patients with dementia (N = 8,395) | Non-AF history (N = 6,716) | With AF history (N = 1,679) | P-value |
|---|---|---|---|---|
| Age at baseline (years) | 82.5 ± 7.36 | 82.5 ± 7.39 | 82.3 ± 7.22 | 0.27 |
| CHA2DS2-VASc | 1.71 ± 1.25 | 1.73 ± 1.25 | 1.78 ± 1.24 | 0.15 |
| Sex: male | 3,996 (47.6%) | 3,216 (47.9%) | 780 (46.5%) | 0.29 |
| Propensity score | 0.993 ± 0.004 | 0.993 ± 0.004 | 0.993 ± 0.004 | >0.99 |
| Duration of AF (years) | Na | Na | 3.74 ± 4.49 | Na |
| Hypertension | 2,749 (32.7%) | 2,286 (34.0%) | 463 (27.6%) | <0.001 |
| Heart failure | 298 (3.55%) | 117 (1.74%) | 181 (10.8%) | <0.001 |
| Diabetes mellitus | 1,025 (12.2%) | 880 (13.1%) | 145 (8.64%) | <0.001 |
| Hyperlipidemia | 411 (4.90%) | 338 (5.03%) | 73 (4.35%) | 0.25 |
| Chronic kidney disease | 214 (2.55%) | 149 (2.22) | 65 (3.87%) | <0.001 |
| Stroke | 2,379 (28.3%) | 1,872 (27.9%) | 507 (30.2%) | 0.06 |
| Coronary artery disease | 31 (0.37%) | 20 (0.30%) | 11 (0.66%) | 0.031 |
| Liver cirrhosis | 31 (0.37%) | 28 (0.42%) | 3 (0.18%) | 0.15 |
| Chronic obstructive pulmonary disease | 417 (4.97%) | 305 (4.54%) | 112 (6.67%) | <0.001 |
| Thyroid disease | 10 (0.12%) | 5 (0.07%) | 5 (0.30%) | 0.018 |
| Sleep apnea | 454 (5.41%) | 362 (5.39%) | 92 (5.48%) | 0.89 |
| Receiving AF ablation | 158 (1.88%) | 0 (0.00%) | 158 (9.41%) | <0.001 |
| Medication uses | ||||
| Anti-arrhythmic drugs | 743 (8.85%) | 325 (4.84%) | 418 (24.9%) | <0.001 |
| Beta-blocks | 2,610 (31.1) | 1,952 (29.1%) | 658 (39.2%) | <0.001 |
| Novel oral anticoagulants | 1,024 (12.2%) | 362 (5.39%) | 662 (39.4%) | <0.001 |
| Warfarin | 625 (7.44%) | 255 (3.35%) | 400 (23.8%) | <0.001 |
AF, atrial fibrillation; N, number; Na, not available.