TABLE 5.
Effect of PSPL extracts on blood biochemistry parameters in the SD male acute toxicity study. Values are expressed as means ± SEM. ALP, alkaline phosphatase; AST, aspartate transaminase; ALT, alanine transaminase; GGT, gamma-glutamyl transferase; AC, acute control group; AT 2000, 2,000 mg/kg of PSPL.
| Parameters | AC | AT 2000 |
|---|---|---|
| Renal function test | ||
| Sodium (mmol/L) | 145.00 ± 1.00 | 145.33 ± 0.88 |
| Potassium (mmol/L) | 10 ± 0 | 9.5 ± 0.5 |
| Chloride (mmol/L) | 97.00 ± 1.53 | 100.67 ± 1.45 |
| Urea (mmol/L) | 8.30 ± 0.21 | 7.60 ± 0.58 |
| Creatinine (mmol/L) | 51.00 ± 4.51 | 44.33 ± 4.41 |
| Liver Function Test | ||
| Total protein (g/L) | 69.33 ± 0.67 | 69.33 ± 2.96 |
| Albumin (g/L) | 40.33 ± 1.20 | 41.00 ± 0.58 |
| Globulin (g/L) | 29.00 ± 0.58 | 28.33 ± 2.40 |
| Albumin–globulin ratio | 1.39 ± 0.07 | 1.46 ± 0.01 |
| ALP (U/L) | 371.00 ± 16.01 | 290.00 ± 52.27 |
| AST (U/L) | 136.00 ± 7.94 | 144.67 ± 29.49 |
| ALT (U/L) | 86.00 ± 8.89 | 92.00 ± 25.03 |
| GGT (U/L) | 1.00 ± 0.00 | 1.00 ± 0.00 |
| Total bilirubin (µmol/L) | 1.00 ± 0.00 | 1.00 ± 0.00 |