Table 1.
Patient Characteristics | n | Median PFS | P | Median OS | P | |
---|---|---|---|---|---|---|
Age | ≤50 years old | 6 | 6 | 0.654 | 21 | 0.721 |
>50 years old | 15 | 13 | 21 | |||
Sex | Male | 19 | 10 | 0.396 | 20 | 0.488 |
Female | 2 | 5 | 15 | |||
Child-Pugh class | A | 14 | 12 | 0.012 | 21 | 0.003 |
B | 5 | 9 | 8 | |||
C | 2 | 2 | - | |||
Tumor thrombus | Yes | 5 | 3 | 0.003 | 24 | 0.598 |
None | 16 | 12 | 21 | |||
KPS | >70 | 11 | 13 | 0.028 | 28 | 0.001 |
60–70 | 10 | 3 | 13 | |||
Liver cirrhosis | Yes | 14 | 8 | 0.153 | 20 | 0.2 |
No | 7 | 12 | 24 | |||
Combination therapy | Yes | 14 | 10 | 0.298 | 24 | 0.038 |
No | 7 | 6 | 20 | |||
Metastatic site | Lung | 10 | 6 | 0.149 | 13 | 0.194 |
Mediastinal/supraclavicular | 3 | 6 | - | |||
Brain | 1 | 17 | - | |||
Adrenal gland | 2 | 3 | - | |||
Bone | 5 | 13 | 8 | |||
Radiotherapy dose | ≤52Gy | 8 | 6 | 0.007 | 13 | 0.038 |
>52Gy | 13 | 12 | 21 | |||
Failure mode | Intrahepatic | 9 | 9 | 0.533 | 14 | 0.032 |
Extrahepatic | 9 | 10 | 28 | |||
Ascites | Yes | 7 | 3 | 0.001 | 13 | 0.001 |
None | 14 | 12 | 24 |
Abbreviations: PFS, progression-free survival; OS, overall survival; KPS, Karnofsky performance status; CIK, cytokine-induced killer.