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. 2023 Apr 12;16:1271–1278. doi: 10.2147/IJGM.S403316

Table 1.

Analysis of Baseline Characteristics of Patients

Patient Characteristics n Median PFS P Median OS P
Age ≤50 years old 6 6 0.654 21 0.721
>50 years old 15 13 21
Sex Male 19 10 0.396 20 0.488
Female 2 5 15
Child-Pugh class A 14 12 0.012 21 0.003
B 5 9 8
C 2 2 -
Tumor thrombus Yes 5 3 0.003 24 0.598
None 16 12 21
KPS >70 11 13 0.028 28 0.001
60–70 10 3 13
Liver cirrhosis Yes 14 8 0.153 20 0.2
No 7 12 24
Combination therapy Yes 14 10 0.298 24 0.038
No 7 6 20
Metastatic site Lung 10 6 0.149 13 0.194
Mediastinal/supraclavicular 3 6 -
Brain 1 17 -
Adrenal gland 2 3 -
Bone 5 13 8
Radiotherapy dose ≤52Gy 8 6 0.007 13 0.038
>52Gy 13 12 21
Failure mode Intrahepatic 9 9 0.533 14 0.032
Extrahepatic 9 10 28
Ascites Yes 7 3 0.001 13 0.001
None 14 12 24

Abbreviations: PFS, progression-free survival; OS, overall survival; KPS, Karnofsky performance status; CIK, cytokine-induced killer.