Table 1.
Trends in the incidence rate and mortality of 44 national notifiable infectious diseases in China from 2010 to 2019
| Disease | Incidence rate (per 100 000) | Mortality (per 100 000) | ||||||
|---|---|---|---|---|---|---|---|---|
| 2010 | 2019 | EAPC (95% CI)* | Trend | 2010 | 2019 | EAPC (95% CI)* | Trend | |
| Respiratory diseases | 109.85 | 340.95 | 6.85% (−1.50 to 15.90) | Stable | 0.2416 | 0.2339 | 0.16% (−3.22 to 3.66) | Stable |
| Measles | 2.86 | 0.21 | −17.13% (−35.27 to 6.09) | Stable | 0.0020 | 0.0000 | −47.29% (−71.94 to −1.01) | Decrease |
| Pertussis | 0.13 | 2.15 | 36.96% (24.45–50.73) | Increase | 0.0001 | 0.0001 | −6.87% (−57.91 to 106.07) | Stable |
| Diphtheria | 0.00 | 0.00 | 0.00% (0.00–0.00) | Stable | 0.0000 | 0.0000 | 0.00% (0.00–0.00) | Stable |
| Meningococcal meningitis | 0.02 | 0.01 | −12.05% (−16.00 to −7.92) | Decrease | 0.0025 | 0.0004 | −15.15% (−21.12 to −8.73) | Decrease |
| Scarlet fever | 1.56 | 5.85 | 10.97% (3.13–19.40) | Increase | 0.0000 | 0.0000 | −44.35% (−75.81 to 28.04) | Stable |
| Tuberculosis | 74.27 | 55.55 | −2.96% (−3.28 to −2.65) | Decrease | 0.2248 | 0.2141 | 0.03% (−3.01 to 3.15) | Stable |
| SARS | 0.00 | 0.00 | 0.00% (0.00–0.00) | Stable | 0.0000 | 0.0000 | 0.00% (0.00–0.00) | Stable |
| Leprosy | 0.03 | 0.02 | −6.57% (−9.28 to −3.79) | Decrease | 0.0003 | 0.0000 | −52.80% (−79.29 to 7.58) | Stable |
| Seasonal influenza | 4.83 | 253.36 | 45.16% (29.81–62.33) | Increase | 0.0005 | 0.0193 | 54.86% (29.45–85.26) | Increase |
| Mumps | 22.37 | 21.48 | −5.78% (−13.39 to 2.50) | Stable | 0.0003 | 0.0000 | −59.23% (−79.46 to −19.09) | Decrease |
| Rubella | 3.23 | 2.33 | −23.22% (−40.28 to −1.28) | Decrease | 0.0001 | 0.0000 | −41.97% (−73.44 to 26.75) | Stable |
| H1N1a | 0.53 | 0.0110 | ||||||
| Intestinal diseases | 213.27 | 242.90 | 2.03% (−0.27 to 4.38) | Stable | 0.0768 | 0.0037 | −27.20% (−32.92 to −20.99) | Decrease |
| Cholera | 0.01 | 0.00 | −17.54% (−28.97 to −4.27) | Decrease | 0.0000 | 0.0000 | −11.80% (−50.58 to 57.41) | Stable |
| Hepatitis A | 2.64 | 1.38 | −7.28% (−9.74 to −4.75) | Decrease | 0.0003 | 0.0002 | −7.04% (−21.80 to 10.51) | Stable |
| Hepatitis E | 1.77 | 2.02 | 0.55% (−0.80 to 1.92) | Stable | 0.0026 | 0.0011 | −10.17% (−16.84 to −2.97) | Decrease |
| Bacterial and amoebic dysentery | 18.90 | 5.81 | −12.66% (−13.35 to −11.95) | Decrease | 0.0027 | 0.0001 | −32.36% (−37.89 to −26.33) | Decrease |
| Typhoid and paratyphoid | 1.05 | 0.66 | −3.93% (−6.14 to −1.68) | Decrease | 0.0002 | 0.0000 | −31.98% (−68.39 to 46.39) | Stable |
| Poliomyelitis | 0.00 | 0.00 | −33.50% (−68.53 to 40.54) | Stable | 0.0000 | 0.0000 | −25.40% (−56.42 to 27.69) | Stable |
| Infectious diarrhea | 55.93 | 95.64 | 5.84% (3.75–7.97) | Increase | 0.0032 | 0.0009 | −9.17% (−14.04 to −4.03) | Decrease |
| Hand, foot, and mouth disease | 132.96 | 137.40 | 1.50% (−2.63 to 5.81) | Stable | 0.0678 | 0.0014 | −32.63% (−40.21 to −24.10) | Decrease |
| Zoonotic infectious diseases | 3.64 | 4.16 | 0.43% (−2.93 to 3.90) | Stable | 0.1609 | 0.0234 | −18.75% (−20.28 to −17.18) | Decrease |
| Plague | 0.00 | 0.00 | −20.20% (−69.52 to 108.87) | Stable | 0.0001 | 0.0001 | −28.76% (−72.13 to 82.08) | Stable |
| Hemorrhagic fever | 0.71 | 0.69 | −1.25% (−4.68 to 2.30) | Stable | 0.0088 | 0.0032 | −9.28% (−14.91 to −3.28) | Decrease |
| Rabies | 0.15 | 0.02 | −19.61% (−20.90 to −18.29) | Decrease | 0.1509 | 0.0198 | −19.80% (−21.14 to −18.44) | Decrease |
| Leptospirosis | 0.05 | 0.02 | −12.44% (−17.60 to −6.95) | Decrease | 0.0008 | 0.0001 | −36.69% (−64.72 to 13.60) | Stable |
| Brucellosis | 2.53 | 3.15 | 1.00% (−3.57 to 5.79) | Stable | 0.0001 | 0.0001 | 13.38% (−53.56 to 176.84) | Stable |
| Hydatid disease | 0.19 | 0.29 | 5.90% (2.02–9.93) | Increase | 0.0001 | 0.0001 | −15.42% (−67.32 to 118.88) | Stable |
| H5N1 | 0.00 | 0.00 | −63.23% (−79.92 to −32.69) | Decrease | 0.0001 | 0.0000 | −58.31% (−76.43 to −26.27) | Decrease |
| H7N9 | 0.00 | −47.11% (−83.81 to 72.80) | – | 0.0001 | −25.37% (−78.72 to 161.70) | – | ||
| Vector‐borne infectious diseases | 0.96 | 1.89 | 3.85% (−11.74 to 22.19) | Stable | 0.0081 | 0.0025 | −5.11% (−14.80 to 5.68) | Stable |
| Typhus | 0.17 | 0.08 | −10.70% (−13.73 to −7.57) | Decrease | 0.0001 | 0.0000 | −41.97% (−75.79 to 39.09) | Stable |
| Japanese encephalitis | 0.19 | 0.03 | −11.71% (−21.68 to −0.47) | Decrease | 0.0069 | 0.0009 | −7.77% (−23.54 to 11.26) | Stable |
| Kala‐azar | 0.03 | 0.01 | −6.62% (−15.28 to 2.93) | Stable | 0.0001 | 0.0000 | −46.63% (−76.87 to 23.13) | Stable |
| Malaria | 0.55 | 0.18 | −8.16% (−13.76 to −2.20) | Decrease | 0.0010 | 0.0014 | −8.59% (−20.39 to 4.96) | Stable |
| Dengue | 0.02 | 1.59 | 56.20% (9.43–122.97) | Increase | 0.0000 | 0.0002 | 137.91% (11.22–408.89) | Increase |
| Filariasis | 0.00 | 0.00 | ‐25.40% (‐56.42~27.69) | Stable | 0.0000 | 0.0000 | 0.00% (0.00~0.00) | Stable |
| Sexual, blood‐borne, and mother‐to‐child‐borne infectious diseases | 126.89 | 139.70 | 0.72% (−0.23 to 1.69) | Stable | 0.6466 | 1.5459 | 8.76% (6.88–10.68) | Increase |
| Hepatitis B | 79.46 | 71.77 | −1.46% (−2.80 to −0.10) | Decrease | 0.0516 | 0.0320 | −6.03% (−10.07 to −1.82) | Decrease |
| Hepatitis C | 11.47 | 16.02 | 2.83% (1.20–4.48) | Increase | 0.0096 | 0.0073 | −3.13% (−6.15 to ‐−0.01) | Decrease |
| Hepatitis D | 0.03 | −5.67% (−10.81 to −0.24) | – | 0.0000 | 0.00% (0.00–0.00) | – | ||
| AIDs | 1.20 | 5.10 | 14.99% (8.75–21.59) | Increase | 0.5801 | 1.5036 | 9.65% (7.71–11.63) | Increase |
| Gonorrhea | 7.91 | 8.45 | 3.00% (0.39–5.67) | Increase | 0.0001 | 0.0000 | −31.39% (−58.46 to 13.30) | Stable |
| Syphilis | 26.86 | 38.37 | 3.31% (2.52–4.11) | Increase | 0.0052 | 0.0030 | −7.96% (−10.40 to −5.45) | Decrease |
| Diseases with other transmission routes | 22.92 | 3.04 | −11.89% (−23.22 to 1.12) | Stable | 0.0644 | 0.0031 | −33.55% (−41.82 to −24.11) | Decrease |
| Anthrax | 0.02 | 0.02 | 2.21% (−2.39 to 7.03) | Stable | 0.0004 | 0.0001 | −5.71% (−16.49 to 6.46) | Stable |
| Neonatal tetanus | 0.79 | 0.04 | −29.76% (−33.14 to −26.20) | Decrease | 0.0640 | 0.0030 | −34.03% (−42.46 to −24.36) | Decrease |
| Schistosomiasis | 0.32 | 0.01 | −32.37% (−52.13 to −4.46) | Decrease | 0.0000 | 0.0000 | −48.38% (−76.38 to 12.80) | Stable |
| Acute hemorrhagic conjunctivitis | 21.78 | 2.97 | −10.12% (−23.26 to 5.27) | Stable | 0.0000 | 0.0000 | 0.00% (0.00–0.00) | Stable |
| Class‐A infectious diseases b | 0.01 | 0.00 | −16.30% (−27.93 to −2.79) | Decrease | 0.0001 | 0.0001 | −37.17% (−72.63 to 44.23) | Stable |
| Class‐B infectious diseases b | 235.99 | 219.08 | −1.05% (−1.56 to −0.54) | Decrease | 1.1258 | 1.7907 | 4.56% (2.44–6.72) | Increase |
| Class‐C infectious diseases b | 241.52 | 513.57 | 6.22% (2.13–10.48) | Increase | 0.0725 | 0.0217 | −14.76% (−23.46 to −5.07) | Decrease |
*If the EAPC estimation and its 95% CIs were both >0 (or both <0), the ASR had an increasing trend (or a decreasing trend).
Abbreviations: 95% CI, 95% confidence interval; AID, acquired immunodeficiency disease; EAPC, estimated annual percent change; SARS, severe acute respiratory syndrome.
a
Influenza A H1N1 first broke out in China in 2009 and its data were combined into seasonal influenza from December 2013.
b
Class‐A infectious diseases include plague and cholera; Class‐B infectious diseases include infectious SARS, AIDs, viral hepatitis (not include hepatitis D), polio, H5N1, measles, hemorrhagic fever, rabies, Japanese encephalitis, dengue, anthrax, bacterial, and amoebic dysentery, tuberculosis, typhoid and paratyphoid, meningococcal meningitis, pertussis, diphtheria, tetanus, scarlet Fever, brucellosis, gonorrhea, syphilis, leptospirosis, schistosomiasis, malaria; Class‐C infectious diseases include seasonal influenza, mumps, rubella, acute hemorrhagic conjunctivitis, leprosy, typhus, kala‐azar, hydatid disease, filariasis, and infectious diarrheal diseases other than cholera, bacterial and amoebic dysentery, typhoid, and paratyphoid.