TABLE 3.
Characteristics of the 6 benign duplications detected with circulating extravillous trophoblasts (cEVTs) single‐cell analysis ranging from 3Mb to 900Kb
| Patient ID | Fetus sex | Genomic location | Copy number | Length (Mb) | Cells with alteration a |
|---|---|---|---|---|---|
| M031 | XX | chrX:6400000–8100000 | 3 | 1.7 | 1 (100%) b |
| M055 | XY | chr4:68000000–71000000 | 3 | 3 | 1 (100%) |
| M074 | XY | chr17:63600000–64600000 | 3 | 1 | 2 (66.7%) |
| M113 | XX | chr7:125200000–126100000 | 3 | 0.9 | 2 (100%) |
| M143 | XX | chr18:47600000–49000000 | 3 | 1.4 | 2 (100%) |
| M156 | XX | chr13:23500000–25400000 | 3 | 1.9 | 3 (100%) |
a
Percentages calculated relative to the total number of high‐quality fetal profiles available.
b
Twin pregnancy with 2 fetal cells were recovered, 1 from each fetus. Alteration was revealed in both cells; however, the cell from twin B was in S phase. Therefore, the call out of the microduplication was not reliable.