Size distribution of adipocyte from retroperitoneal (RP) adipose tissue
of rats. Between 4 and 19 weeks of age, rats were fed low- and high-fat
diets, respectively. Thereafter, rats in each dietary group received
drinking water containing either 1.51% l-arginine·HCl or 2.55%
l-alanine (isonitrogenous control) for 12 weeks. At the end
of the feeding experiment, RP adipose tissue was dissected, adipocytes
were isolated using an enzymatic method, and their sizes were determined
under a microscope. Data are expressed as means ± SEM
(n = 8/treatment group). P values
for diet effect, AA effect, and their interaction are summarized
below: