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. 2022 Dec 1;259(1):103–114. doi: 10.1002/path.6026

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© 2022 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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PD‐L1 and CTL expression in PPGL. (A) Representative images of PD‐L1 immunohistochemistry performed in PPGL showing absence (a) or presence of homogenously (b) or focally (c and d) distributed staining of PD‐L1. Positive immunostaining is localized at plasma membrane and cytoplasm of tumor cells. Scale bars, 50 μm. (B) Representative images of CD8 immunohistochemistry performed in PPGL showing tumors with cold (a and b), hot (c), or immune‐excluded (d) phenotypes. Images below (c) and (d) are magnified pictures of the areas outlined in (c) and (d), respectively. Scale bars, 100 μm.