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. 2023 Jan 11;65(2):e22360. doi: 10.1002/dev.22360

TABLE 9.

Summary of infant gut microbiome biomarkers outcomes across neurodevelopmental domains (N = 13)

Infant gut microbiome biomarker genus Alpha diversity Beta diversity Aquificae Firmicutes Bacteroidetes Actinobacteria Proteobacteria Verrucomicrobia Coriobacteriaceae
# Studies 42 5 1 51 11 14 13 1 2
C 5↓, 10– 1– 21– 5– 1↑, 3– 3–
L 1↓ 1↓, 3– 1– 1– 2–
M 1↓, 6– 1– 19– 4– 4– 3–
E 2↑, 11↓ 1↑, 2↓ 12↓, 4– 1↓, 1– 1↕, 1↑, 3↓, 1– 1↓, 2–
S 2– 1↓, 3– 1↑, 4– 1– 1–
T 5↑, 2↓, 7– 1↑ 1– 3↑, 9– 2↑, 1↓, 2– 1↑, 3– 1↑, 1↓, 1– 1↓

Note: C, cognitive domain; L, language domain; M, motor domain; A, adaptive behavior domain; E, emotional domain; S, social domain; T, temperament.