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. 2022 Dec 15;37(1):e22681. doi: 10.1096/fj.202200253R

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© 2022 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Data integration for a comprehensive whole‐cell model of pancreatic beta cells (from White et al., 2020 ³⁸ ©, some rights reserved; exclusive licensee AAAS; distributed under a CC BY‐NC 4.0 License (http://creativecommons.org/licenses/by‐nc/4.0/). (A) Imaging data from SXT ³⁸ and cryo‐ET ⁹⁴ of INS‐1 E rat insulinoma pancreatic beta cells showing details of information at different spatial scales. (B) Structural features of the insulin crystal of cells (insulin structural model ⁹⁵ ; PDB ID: 2OM0). (C) Model of the cell produced in CellPack (http://cellPACK.org/), based on information from (A) and (B).