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. 2023 Mar 3;14(4):514–520. doi: 10.1021/acsmedchemlett.2c00491

Table 2. C–N Coupling Reaction Results Using ChemBeads Prepared by Different Coating Methods.

coating method actual loading (w/w) bead mass (mg) actual reagent mass (mg) percent conversion
free catalyst     0.5 82
RAM 4.61 10 0.46 89
hand mixing 3.96 10 0.39 89
vortex mixer 5.01 10 0.50 85
mini vortex mixer 4.31 10 0.43 83