Syntheses of BODIPY-labeled
fluorescent probes 14–17. Reagents
and conditions: (a) Cs2CO3, DMF, at 50 °C
overnight, 34–47% (b) 2-(prop-2-yn-1-yloxy)ethan-1-ol,
PPh3, DIAD, THF, from 0 °C to room temperature overnight,
35%. (c) CuSO4·5H2O, sodium ascorbate,
THF: H2O (1:1, v/v), at 50 °C overnight, 73–81%.
(d) LiOH, H2O: MeOH (1:1, v/v), at room temperature for
2 h, 65–81%.