An enriched environment (EE) mitigates neurologic deficits and
motor function after ICH. (a) Accommodation in an EE decreased
the neurologic deficit scores of mice on days 3, 5, 7, and 14
after ICH. n = 10–13 mice/group. *p < 0.05
vs. sham group; #p < 0.05 vs. ICH
group(repeated measures ANOVA followed by Bonferroni's post hoc
test). (b) ICH mice exposed to EE performed better in the corner
turn test than ICH mice exposed to the standard environment (SE)
on days 3, 5, and 7 after ICH. n = 13 mice/group.
*p < 0.05 vs. sham group;
#p < 0.05 vs. ICH + SE
group (repeated measures ANOVA followed by Bonferroni's post hoc
test). (c) ICH mice exposed to EE performed better in the
forelimb placement test than ICH mice exposed to SE on days 3,
5, 7 and 14. n = 10 mice/group. *p < 0.05
vs. sham group; #p < 0.05 vs.
ICH + SE group (repeated measures ANOVA followed by Bonferroni’s
post hoc test) and (d) ICH mice exposed to EE had a better motor
performance on the hindlimb placement test than ICH mice exposed
to SE on days 3, 5, and 7. n = 10 mice/group.
*p < 0.05 vs. sham group;
#p < 0.05 vs. ICH + SE
group (repeated measures ANOVA followed by Bonferroni’s post hoc
test). Values are mean ± SD.