Scheme 4. Synthesis of Compounds 14a–j.
Reagents and conditions: (a) BOC2O, DIEA, DCM; (b) EDCI, NH4Cl, DIEA, DCM; (c) HCl in 1,4-dioxane; (d) EDCI, DIEA, DCM 0 °C (5 min), rt (18 h).
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