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| compound | R1 | DCAF1 KD (nM)a |
|---|---|---|
| 14a | H | NB |
| 3b | (S) Ph | 16,400; 16,900 |
| 14b | (S) 2-Cl Ph | 22,960; 21,940 |
| 14c | (S) 3-Cl Ph | 4220; 4000 |
| 14d | (S) 4-Cl Ph | 6900; 6800 |
| 14e | (S) 2-F Ph | 15,500; 15,800 |
| 14f | (S) 3-F Ph | NB |
| 14g | (S) 4-F Ph | 9600; 9800 |
| 14h | (S) 2-OMe Ph | NB |
| 14i | (S) 3-OMe Ph | NB |
| 14j | (S) 4-OMe Ph | NB |
Experiments were performed in duplicate.
