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. 2023 Jan 25;9(1):e200048. doi: 10.1212/NXG.0000000000200048

Figure 6. Seahorse Analysis on Cultured Skin Fibroblasts.

Figure 6

(A) Maximal respiration and spare respiratory capacity are decreased in fibroblasts from affected siblings (COQ7) compared with their carrier father and sibling (control). (B) Basal extracellular acidification rate, a proxy measure of glycolysis, is higher in fibroblasts from affected siblings. (C) The rate of ATP formation from OXPHOS and glycolysis. (D) The supply flexibility index. All values are presented as mean values ± SD. Comparisons between groups were as determined using a 2-tailed Student t test for independent samples. *p < 0.05, **p < 0.01.