Table 1.

Characteristic Table of Included Articles.

Study	Type of research	Number of original studies (items)	Original study sample size (cases)	Interventions		Risk of bias assessment tool	Closing indicators	Main conclusions
				Control group	Test group
Yu et al 15	RCT	19	1705	Anthracycline-containing chemotherapy regimens	Anthracycline chemotherapy regimen + herbal injection	Cochrane Risk of Bias Assessment Tool	②③④⑧⑨	Chinese herbal injection is effective against cardiotoxicity caused by anthracycline chemotherapy regimen.
Long et al 16	RCT	8	486	Anthracycline-containing chemotherapy regimens	Anthracycline-based chemotherapy regimen + Ginseng-Qi Fuzheng injection	Cochrane Risk of Bias Assessment Tool	③④⑧⑩	Shenqi Fuzheng injection can improves cardiac function in patients on anthracycline chemotherapy regimens.
Ma et al 17	RCT	8	660	Anthracycline-containing chemotherapy regimens	Anthracycline-based chemotherapy regimen + cardiac veinron injection	Cochrane Risk of Bias Assessment Tool	③④⑤⑥⑨	Cardioplegia injection is effective in reducing the rate of ECG abnormalities in patients treated with anthracycline chemotherapy regimens.
Zhang et al 18	RCT	12	775	Anthracycline-containing chemotherapy regimens	Anthracycline chemotherapy regimen + Shenmai injection	Cochrane Risk of Bias Assessment Tool	①②	Shenmai injection is effective in the treatment of acute leukemia and can alleviate the adverse effects caused by chemotherapy.
Ma et al 19	RCT	10	612	Anthracycline-containing chemotherapy regimen +  dexrazoxane	Anthracycline chemotherapy regimen +  dexraxozane + Shenmai injection	Cochrane Risk of Bias Assessment Tool	③④⑧⑩	Combination of dexrazoxane with Shenmai injection is superior to dexrazoxane alone in preventing anthracycline chemotherapy-induced cardiotoxicity.
Yang et al 20	RCT	6	615	Anthracycline-containing chemotherapy regimen +  vitamin E and coenzyme Q, etc.	Anthracycline-containing chemotherapy regimens + Biovein injection	Cochrane Risk of Bias Assessment Tool	③⑤⑥⑦	Shengmai injection may prevent cardiotoxicity caused by anthracycline chemotherapy drugs.
Li 21	RCT	24	1702	Anthracycline-containing chemotherapy regimens	Anthracycline chemotherapy regimen + herbal injection	Jadad Scale	③④⑧⑨	Chinese herbal injections are protective against cardiotoxicity caused by anthracycline-based chemotherapy regimens

① Clinical effective rate, ② Cardiac toxicity, ③ Abnormal rate of ECG, ④ Left ventricular ejection fraction, LVEF, ⑤ Change of left ventricular end diastolic diameter, LVIDD, ⑥ Change of left ventricular end systolic diameter, LVISD, ⑦ Change of left ventricular short axis shortening rate, FS, ⑧ Creatine kinase isoenzyme-MB, CK-MB, ⑨ Cardiac troponin I, cTnI, ⑩ Type B natriuretic peptide, BNP.

Abbreviations: RCT, randomized controlled trial.