Table 4.
Inclusion of Literature Outcome Measure GRADE Score.
| Closing indicators | First author | Evidence quality evaluation factors (points) | Quality of Evidence | ||||
|---|---|---|---|---|---|---|---|
| Risk of bias | Inconsistency | Indirectness | Imprecision | Publication bias | |||
| Clinical validity | Zhang et al 18 | −1a | 0 | 0 | 0 | −1d | Low |
| Cardiotoxicity | Yu et al 15 | −1a | 0 | 0 | −1c | −1d | Extremely low |
| Zhang et al 18 | −1a | 0 | 0 | 0 | −1d | Low | |
| Abnormal electrocardiogram rate | Yu et al 15 | −1a | 0 | 0 | 0 | −1d | Low |
| Long et al 16 | −1a | 0 | 0 | −1c | −1d | Extremely low | |
| Ma et al 17 | −1a | 0 | 0 | 0 | −1d | Low | |
| Ma et al 19 | −1a | 0 | 0 | 0 | −1d | Low | |
| Yang et al 20 | −1a | 0 | 0 | 0 | −1d | Low | |
| Li 21 | −1a | 0 | 0 | 0 | 0 | Moderate | |
| Left ventricular ejection fraction (LVEF) | Yu et al 15 | −1a | 0 | 0 | 0 | −1d | Low |
| Long et al 16 | −1a | −1b | 0 | 0 | −1d | Extremely low | |
| Ma et al 17 | −1a | 0 | 0 | 0 | −1d | Low | |
| Ma et al 19 | −1a | −1b | 0 | 0 | −1d | Extremely low | |
| Li 21 | −1a | −1b | 0 | 0 | −1d | Extremely low | |
| Left ventricular end-diastolic internal diameter (LVIDD) | Ma et al 17 | −1a | 0 | 0 | −1c | −1d | Extremely low |
| Yang et al 20 | −1a | 0 | 0 | −1c | −1d | Extremely low | |
| Left ventricular end-systolic internal diameter (LVISD) | Ma et al 17 | −1a | −1b | 0 | −1c | −1d | Extremely low |
| Yang et al 20 | −1a | 0 | 0 | −1c | −1d | Extremely low | |
| Left ventricular short axis shortening rate (FS) | Yang et al 20 | −1a | 0 | 0 | −1c | −1d | Extremely low |
| Creatine kinase isoenzyme-MB (CK-MB) | Yu et al 15 | −1a | 0 | 0 | 0 | −1d | Low |
| Long et al 16 | −1a | −1b | 0 | −1c | −1d | Extremely low | |
| Ma et al 19 | −1a | 0 | 0 | −1c | −1d | Extremely low | |
| Li 21 | −1a | −1b | 0 | 0 | −1d | Extremely low | |
| Troponin I (cTnI) | Yu et al 15 | −1a | 0 | 0 | 0 | −1d | Low |
| Ma et al 17 | −1a | −1b | 0 | 0 | −1d | Extremely low | |
| Li 21 | −1a | −1b | 0 | 0 | −1d | Extremely low | |
| B-type natriuretic peptide (BNP) | Long et al 16 | −1a | −1b | 0 | −1c | −1d | Extremely low |
| Ma et al 19 | −1a | 0 | 0 | −1c | −1d | Extremely low | |
a indicates the risk of bias in the random method, allocation concealment, blind method and loss of follow-up. b indicates that there was large heterogeneity between studies and no reasonable measures were taken to reduce heterogeneity, such as subgroup analysis or sensitivity analysis. c indicates that the sample size is small and the confidence interval is wide. d indicates that the funnel plot was asymmetric, or there were fewer than 9 included studies, or all of them were positive results, so the possibility of publication bias was high.