Table 2.
Association between NAFLD and the incident CKD diagnoses in patients followed in general practices in Germany (Cox regression models)
Cohort | Univariable Cox regression | Multivariable Cox regressiona | ||
---|---|---|---|---|
Cohort | Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value |
Total | 1.80 (1.73–1.86) | < 0.001 | 1.90 (1.83–1.97) | < 0.001 |
Age 18–50 | 2.13 (1.91–2.37) | < 0.001 | 2.20 (1.98–2.46) | < 0.001 |
Age 51–60 | 1.88 (1.73–2.05) | < 0.001 | 1.98 (1.82–2.15) | < 0.001 |
Age 61–70 | 1.73 (1.62–1.85) | < 0.001 | 1.82 (1.70–1.94) | < 0.001 |
Age > 70 | 1.66 (1.56–1.95) | < 0.001 | 1.72 (1.63–1.83) | < 0.001 |
Women | 1.85 (1.76–1.95) | < 0.001 | 1.93 (1.83–2.03) | < 0.001 |
Men | 1.74 (1.66–1.83) | < 0.001 | 1.87 (1.78–1.97) | < 0.001 |
aMultivariable Cox regression adjusted for prescriptions of insulin, diuretics, beta blockers, calcium channel blockers, ACE inhibitors, and angiotensin II receptor blockers