Fig. 5.

Simvastatin suppressed LOHP-induced neuropathy. a, b Cold sensitivity was analyzed using a hot/cold plate. Mean values and S.E.M. are shown. Statistical analysis was performed by ANOVA with Dunnett’s, and the difference was considered significant when P < 0.05. c, d Mechanical allodynia was analyzed using the von Frey filaments (Ugo Basile) with bending forces (0.16 g). Mean values and S.E.M. are shown. Statistical analysis was performed by ANOVA with Dunnett’s, and the difference was considered significant when P < 0.05