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. 2023 Apr 17;23:349. doi: 10.1186/s12885-023-10777-7

Fig. 3.

Fig. 3

Standardised incidence ratio (SIR) of second primary cancer according to the cancer site of the first primary cancer and its of second primary cancer. SIRs for all cancers (on y axis) are classified by their value on x axis. The thresholds of SIR significantly higher than 1 have been defined according to quartiles of their values. The 5% cut-off on that many values can result in false positive or false negative classification