Table 2.
Differences based on VO2Maximum in Patients with a Maximal CPET.
| Total Sample | VO2 peak > 84% pred | VO2 peak ≤ 84% predicted | p-value | |
|---|---|---|---|---|
| n (%) | 19 | 13 | 6 | |
| Age, years | 54 (15.9) | 52 (18.7) | 58.3 (6.2) | 0.287 |
| Sex (%) | 0.735 | |||
| Male | 9 (47.4) | 7 (53.8) | 2 (33.3) | |
| Female | 10 (52.6) | 6 (46.2) | 4 (66.7) | |
| Race (%) | 0.105 | |||
| FVC % pred | 79.8 (15.8) | 85.6 (12.9) | 67.2 (14.8) | 0.028 |
| FEV1% pred | 85.4 (14) | 91 (9.6) | 73.3 (15.1) | 0.035 |
| FEV1/FVC | 84.3 (6.8) | 83.5 (6.1) | 85.8 (8.5) | 0.57 |
| PEF % pred | 98 (17.5) | 104.4 (16.8) | 84.2 (9.3) | 0.004 |
| Performance | ||||
| VO2peak (ml/kg/min) | 22.6 (7.2) | 25.4 (6.2) | 16.4 (5.4) | 0.008 |
| VO2peak (ml/kg/min) % pred | 100 (78–106) | 105 (100–108) | 72 (58–75.5) | < 0.001 |
| VO2 AT (ml/kg/min) | 12.1 (3.8) | 13.5 (3.4) | 9.1 (2.8) | 0.012 |
| VO2 AT/peak % pred | 54.5 (9.8) | 53.5 (9.3) | 56.8 (11.2) | 0.500 |
| Actual MET | 6.4 (2.1) | 7.2 (1.8) | 4.7 (1.5) | 0.011 |
| MET pred | 7.9 (3.4) | 8.9 (2.9) | 5.7 (3.5) | 0.083 |
| Test Duration (n = 15) | 7.8 (2.3) | 8.3 (2.0) | 4.5 (0.0) | 0.019 |
| Test Duration % pred (n = 15) | 86.5 (23.4) | 91.4 (20.9) | 54.8 (9.9) | 0.033 |
| Circulation | ||||
| Peak systolic | 154.2 (22.8) | 159.7 (24.3) | 140 (9.4) | 0.025 |
| Peak diastolic | 71 (70–80) | 72 (70–80) | 70 (70–72) | 0.644 |
| HR reserve (beats/min) | 16 (2–25.5) | 5 (0–16) | 33 (25.2–46.8) | 0.002 |
| HR peak | 150.3 (24.3) | 161.5 (19.7) | 126 (12.9) | < 0.001 |
| HR % pred | 90.4 (10.9) | 96.1 (6.7) | 78.2 (7.4) | < 0.001 |
| HR AT | 102.6 (13.6) | 105.2 (14.4) | 97 (10.5) | 0.183 |
| HR peak % pred | 69 (7.7) | 65.5 (6.3) | 76.7 (4) | < 0.001 |
| Cardiovascular Function | ||||
| Peak VO2/HR | 11.9 (10.1–13.7) | 11.9 (10.7–13.8) | 11.2 (9.7–13.3) | 0.483 |
| O2 pulse peak % pred | 77.4 (18.9) | 79.9 (19.6) | 72 (17.4) | 0.396 |
| VO2/HR AT | 9.9 (8.8–11.4) | 11.1 (9.3–11.9) | 9.4 (6.8–9.9) | 0.105 |
| VO2/HR % pred | 100.9 (15.6) | 107.1 (10.7) | 87.7 (17.1) | 0.039 |
| Rate-pressure product (RPP) | 22,764 (17,503.5–27654) | 25,110 (22,680–29070) | 17,082 (14,850–17290) | 0.008 |
| Ventilation | ||||
| Peak VE (L/min) | 80.2 (24.2) | 87.3 (25.1) | 64.7 (13.3) | 0.02 |
| VE % pred | 86 (19.5) | 88.5 (20.2) | 80.5 (18.1) | 0.405 |
| VE reserve (L/min) | 14 (2–24.5) | 17 (0–24) | 10.5 (4–26) | 0.86 |
| Gas exchange | ||||
| VE/VCo2 AT | 33.4 (7.8) | 31.3 (6.8) | 38 (8.4) | 0.122 |
| RER peak | 1.2 (0.1) | 1.2 (0.1) | 1.1 (0.03) | 0.004 |
Note. AT: Anaerobic threshold. HR: heart rate. Lbs: pounds. FVC: forced vital capacity. Min: minutes. O2: oxygen; pred: predicted. PEF: peak expiratory flow. RER: respiratory exchange ratio at end of test. RPP: rate-pressure product. VE: minute ventilation. VE/VCo2 AT: ventilatory equivalent for carbon dioxide. VO2: oxygen uptake; VO2/HR: oxygen pulse. VE/VCO2 ratio: ventilatory equivalent for carbon dioxide.