Table 13.

List of toxicological studies with the NF

Reference	Type of study	Test system	Dose
Study No. 997‐471‐5889 (Vértesi, 2021)	Bacterial reverse mutation test (GLP, OECD TG 471)	S. Typhimurium TA98, TA100, TA1535 and TA1537 and E. coli WP2 uvrA	Up to 5,000 μg/plate (absence and presence of S9 mix)
Study No. 997‐487‐5890 (Fekete, 2021)	In vitro mammalian cell micronucleus test (GLP, OECD TG 487)	L5178Y tk+/ 3.7.2c (IVGT) mouse lymphoma cell line	Up to 400 ug/mL (absence of S9 mix) and up to 600 ug/mL (presence of S9 mix)

bw: body weight; GLP: Good Laboratory Practice; OECD TG: Organisation for Economic Co‐operation and Development Test Guideline.