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. 2023 Apr 17:1–15. Online ahead of print. doi: 10.1038/s41577-023-00858-w

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Fig. 3 — a, In the presence of complement, neutralizing antibody (nAb)-coated virions are susceptible to enhanced neutralization (by steric hindrance) and to complement-mediated lysis. b, In the presence of crystallizable fragment receptor (FcR)-bearing effector cells, nAb-coated virions can be sequestered and prevented from binding to host cells or can be taken up by effector cells such as macrophages by antibody-dependent cellular phagocytosis (ADCP). c, Virus-infected cells coated with nAbs are susceptible to killing by effector cells such as natural killer (NK) cells through FcR-dependent, antibody-dependent cellular cytotoxicity (ADCC).