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. 2022 Dec 2;16(4):e014963. doi: 10.1161/CIRCIMAGING.122.014963

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© 2023 The Authors.

Circulation: Cardiovascular Imaging is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited and is not used for commercial purposes.

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Figure 4. — Abnormal valve-related mechanics relate to myocardial fibrosis and ventricular arrhythmia in mitral valve prolapse. Mitral valve prolapse potentially provokes mechanical stress on basal wall adjacent to papillary muscle (right schema), which relates to fibrosis and abnormal myocardial deformation (middle). Both fibrosis and the Double-peak strain pattern (DPP) were associated with ventricular arrhythmic events (left, Kaplan-Meier curves). AO indicates aorta; LA, left atrium; LGE, late gadolinium enhancement; LV, left ventricle; PM, papillary muscle.