Table 3.
Association Between the Presence of Adverse Neonatal Outcomes and HSI Status (Elevated >36 Vs Non-Elevated ≤36)
| Adverse Neonatal Outcomes | Unadjusted OR (95% CI) | p-value | Adjusted ORa (95% CI) | p-value |
|---|---|---|---|---|
| Pre-term birth | 1.474 (0.975–2.230) | 0.05 | 1.318 (0.761–2.283) | 0.32 |
| SGA | 1.408 (0.991–2.002) | 0.06 | 1.334 (0.935–1.904) | 0.11 |
| LGA | 0.980 (0.707–1.359) | 0.61 | 0.918 (0.658–1.279) | 0.61 |
| Neonatal hypoglycemia | 2.802 (1.419–5.536) | < 0.01 | 1.835 (0.910–3.699) | 0.09 |
| Admission to neonatal HDU | 1.499 (1.110–2.023) | 0.01 | 1.008 (0.664–1.532) | 0.97 |
| Compositeb | 1.277 (1.032–1.581) | 0.02 | 1.165 (0.935–1.451) | 0.17 |
Notes: Bold text indicates significance at the p<0.05 level. aAdjusted for maternal age, ethnicity, pre-pregnancy BMI, primiparous status, smoking, GDM, IOL, cesarean delivery and whether liver enzymes were collected during pregnancy. bComposite adverse neonatal outcomes include one or more of pre-term birth, SGA, LGA, neonatal hypoglycemia or admission to neonatal HDU.
Abbreviations: HSI, hepatic steatosis index; OR, odds ratio; CI, confidence intervals; SGA, small-for-gestational age; LGA, large-for-gestational age; HDU, high dependency unit; BMI, body mass index; GDM, gestational diabetes mellitus; IOL, induction of labor.