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Summary characteristics of the included studies.
| Characteristics | No. of studies (no. of participants) |
|---|---|
| Eligible studies | |
| Total no. of trials (no. of participants) | 17 (19,516) |
| Follow‐up at least three years | 11 (12,761) |
| Total no. of outcome events | 2134 |
| Median (IQR) % female | 53 (49–59) |
| Median (IQR) age (years) | 74 (65–80) |
| Country | |
| American | 12 (17,041) |
| European | 4 (2335) |
| China | 1 (140) |
| Inflammatory markers | |
| CRP | 11 (14,324) |
| IL‐6 | 15 (18,710) |
| TNF‐α | 5 (7183) |
IQR, interquartile range.
