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The experimental procedure (A) and postsurgical pain to preexposure to short-term chronic unpredictable stress in mice (B–E). (B, C) Mechanical allodynia test. (D, E) Cold allodynia test. (B, D) Responses of ipsilateral paws. (C, E) Responses of contralateral paws. Results are expressed as mean ± SEM. *P < .05, **P < .01 vs the corresponding time points in the incision plus control group (n = 10/group).
