TABLE 1.

Relationship between widespread pain index and associated symptom scores

		No. pain regions present
	PROMIS 29+2 category	0 regions (24.3%, n=58)	1 region (16.3%, n=39)	2–3 regions (33.2%, n=79)	4 or more regions (26.0%, n=62)	p
Higher scores are worse	Symptoms	Mean + SD
	Pain Interference	46.15±5.40	52.56±3.84	56.79±3.07	60.99±2.78	<0.001
	Depression/Sadness	47.17±4.94	50.50±4.34	54.09±3.69	56.46±3.49	<0.001
	Anxiety/Fear	49.08±4.74	52.25±4.15	54.86±3.79	58.23±3.37	<0.001
	Fatigue	49.74±3.02	54.27±2.67	59.40±2.74	62.31±2.83	<0.001
	Sleep Disturbance	49.31±3.61	52.00±3.56	54.64±3.37	56.70±3.44	<0.001
Lower scores are worse	Functions	Mean + SD
	Cognitive Function	54.49±6.32	51.69±5.85	50.09±5.76	47.58±5.82	<0.001
	Physical Function	50.74±5.46	45.44±3.86	41.55±3.31	38.49±3.15	<0.001
	Ability to Participate in Social Roles/Activities	55.86±4.01	51.12±2.98	46.32±2.78	44.98±2.80	<0.001
Higher worse	PAIN Intensity PROMIS3a	41.58±4.86	49.70±4.04	54.55±3.76	59.53±3.77	<0.001

Abbreviation: PROMIS, Patient-reported Outcome Measurement Information System.