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. Author manuscript; available in PMC: 2023 Apr 17.
Published in final edited form as: J Alzheimers Dis. 2021;80(4):1603–1612. doi: 10.3233/JAD-200323

Table 1.

Summary of cases including clinical, imaging, and clinicopathological diagnosis

Case 1 Case 2 Case 3 Controls
Age at symptom onset (y) 62 58–60 81 N/A
Age at death (y) 68 67 84 72.7SD 17.6
AV-45 findings Positive for amyloid Positive for amyloid Positive for amyloid N/A
AV-133 findings Bilateral caudate and putamen dopaminergic depletion Normal Dopaminergic depletion in center putamen and 3/5 readers noted a decrease in right putamen as well N/A
Clinical diagnosis at PET imaging DLB AD DLB N/A
Clinicopathological diagnosis DLB and AD DLB and AD MSA and AD Cognitively normal
Time between symptoms and imaging 5 y 5 y 3 y N/A
Time between PET imaging and death 22 mo 30 mo 1–2 wk N/A
Postmortem interval 3.0 h 3.1 h 2.5 h 4.0 h SD 0.8
NIA-AA ADNC High ADNC Intermediate ADNC Intermediate ADNC Not AD (1) Low AD (2)
Lewy body stage Neocortical Neocortical N/A (MSA) All Stage 0

NIA-AA ADNC, National Institute on Aging-Alzheimer’s Association Alzheimer’s Disease Neuropathological Change Level; Lewy body stage, Unified Staging System for Lewy Body Disorders stage level; N/A, not applicable.