Fig. 3.

Associations between GC medication dose in mg/m²/day and brain volumes. A higher GC replacement dose in mg/m2/day was associated with reduced volume of the (A) left lingual (B = −106.28, q = 0.045), (B) rostral anterior cingulate (ACC) (B = −59.45, q = 0.033), and (C) right supramarginal gyrus (B = −177.30, q = 0.045), but not when correcting for intracranial volume (ICV). D) GC replacement dose in mg/m²/day was associated with reduced total brain volume (B = −8383, P = 0.027), even when correcting for height (B = −7124, P = 0.45).