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. 2023 Apr 17;14:2196. doi: 10.1038/s41467-023-37975-y

Fig. 2. Biodiversity alteration of the gut virome community after H. pylori eradication therapy.

Fig. 2

a–c Comparisons of alpha diversity indices in virus richness (a), Shannon index (b), and Simpson index (c) among the three groups (BL: N = 44; 6 W: N = 44; 6 M: N = 33; N, the number of patients in each group). Two-sided Wilcoxon tests followed by BH correction were applied. d Principal Coordinate Analysis (PCoA) of the gut virome community among the three groups (BL: N = 44; 6 W: N = 44; 6 M: N = 33). Assessed via PERMANOVA test followed by p-value correction (BH method). e Comparison of the virome community dissimilarity distance at virus species level between baseline, 6-week and 6-month (BL: N = 44; 6 W: N = 44; 6 M: N = 33). The boxes denote the lower 25% quantile, upper 75% quantile, and center line the median, with whiskers extending to a limit of ±1.5 interquartile ranges (IQRs). All the tests were two-sided with BH method for multiple comparisons correction.