Table 5.
Histopathological assessment of the organ tissues using our grading system
| Control | 0.0025 × noael | Number of affected subjects | 0.01 × NOAEL | Number of affected subjects | 0.05 × NOAEL | Number of affected subjects | |
|---|---|---|---|---|---|---|---|
| Testis | I (5/5) | IIc | 3/5 | IIIc | 4/5 | IVc | 5/5 |
| Liver | I (10/10) | IIc | 9/10 | IIIc | 9/10 | IVc | 10/10 |
| Heart | I (10/10) | IIa | 8/10 | IIIa | 7/10 | IVa | 9/10 |
| Lung | I (10/10) | IIa | 9/10 | IIIc | 10/10 | IVc | 10/10 |
| Muscle | I (10/10) | IIa | 7/10 | IIIa | 8/10 | IVa | 6/10 |
| Brain | I (10/10) | IIa | 8/10 | IIIc | 7/10 | IVb | 8/10 |
| Kidney | I (10/10) | IIc | 10/10 | IIIc | 10/10 | IVc | 10/10 |
| Stomach | I (10/10) | IIc | 8/10 | IIIc | 9/10 | IVb | 8/10 |
| Pancreas | I (10/10) | IIb | 7/10 | IIIc | 7/10 | IVb | 8/10 |
| Spleen | I (10/10) | IIc | 7/10 | IIIc | 9/10 | IVc | 7/10 |