Table 2.
Hemodynamic definition of pulmonary hypertension
| Definition | Characteristics | Clinical Groups of PH (see TABLE 1) |
|---|---|---|
| Pulmonary hypertension (PH) | mPAP > 20 mmHg | Groups 1–5 |
| Precapillary PH | mPAP > 20 mmHg | Group 1: Pulmonary arterial hypertension (PAH) |
| PAWP ≤ 15 mmHg | Group 3: PH associated with lung diseases and/or hypoxia | |
| PVR > 2 WU | Group 4: PH associated with pulmonary artery obstructions | |
| Group 5: PH with unclear and/or multifactorial mechanisms | ||
| Isolated postcapillary PH (IpcPH) | mPAP > 20 mmHg | Group 2: PH associated with left heart disease |
| PAWP > 15 mmHg | Group 5: PH with unclear and/or multifactorial mechanisms | |
| PVR < 2 WU | ||
| Combined pre- and postcapillary PH (CpcPH) | mPAP > 20 mmHg | Group 2: PH associated with left heart disease |
| PAWP > 15 mmHg | Group 5: PH with unclear and/or multifactorial mechanisms | |
| PVR > 2 WU | ||
| Exercise PH | mPAP/CO slope between rest and exercise > 3 mmHg/L/min |