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. 2022 Nov 24;103(3):1827–1897. doi: 10.1152/physrev.00030.2021

Table 3.

Formula and equations commonly used to calculate PVR and PAP

Equations Definition Reference(s)
PAP = PVR × CO Where PVR is the vascular resistance of the whole lung including the pulmonary arteries (PVRA), capillaries (PVRC), and veins (PVRV) and CO is cardiac output (3335)
PVR = PVRA + PVRC + PVRV
PAP = CO × (PVRA + PVRC + PVRV)
Hagen–Poiseuille equation (or the Poiseuille law)
Q = ΔP × [(πr4) ÷ (8ηL)] Where Q is flow; π is the constant of 3.14; ΔP is the pressure difference, r is the inner radius of the cylindrical tube (e.g., blood vessel), η is the viscosity of the fluid (e.g., blood), and L is the length of the tube (e.g., the total the blood vessel tree) (3335)
PVR = ΔP ÷ Q (in mmHg·min/L) Where ΔP is the difference between pulmonary arterial pressure (PAP) and left atrial pressure or pulmonary arterial wedge pressure (PAWP), and Q is cardiac output (CO). (35)
PVR = (PAP – PAWP) ÷ CO
PVR = (8Lη) ÷ (πr4) (in dyn/cm5) Where L is the total length of the pulmonary vasculature, η is the viscosity of the venous blood through the lung circulation, π is the constant (3.14), and r is the radius of the lumen of pulmonary vessels (35)