Table 1.

Model inputs applied to the disease impact model.

	Model input
Parameter	18-64 y	≥65 y	Source
Base case analysis
US male population in 2022, No.	101,599,370	26,727,557	US Census Bureau20
Average mortality rates, %	0.4	13.4	Centers for Disease Control and Prevention40
US insured population, %	88.1	99.0	US Census Bureau21
US insured population with ED diagnosis, %	10.0	6.2	Administrative claims data analysis
Diagnosed population not receiving any ED treatment paid for by primary insurance, %	94.0	99.5	Administrative claims data analysis
US male population with moderate to severe ED, %	18.2		Rhoden et al24
US male population with any contraindications for penile prosthesis implantation, %	1.0		Assumption based on US penile prosthesis manufacturer instruction for use25,26 and American Urological Association guideline10 contraindications of treatable/transient infections

Abbreviation: ED, erectile dysfunction.