Effect of tardive dyskinesia status, smoking status, rs4680, rs1076560 and their interactions on Aligned Rank Transformed Abnormal Involuntary Movement Scale (AIMSart) score of tardive dyskinesia. A full factorial ANOVA model identified main effects of (a) tardive dyskinesia status, (b) smoking status and (c) rs4680 (COMT) to have an effect on AIMSart score of tardive dyskinesia. Further, interactions of (d) tardive dyskinesia status and smoking status, smoking status with (e) rs1076560 (DRD2) and (f) rs4680 were also found to have a significant effect on AIMSart score of tardive dyskinesia. #, $ and & represents significantly different from first, second and third bars post-Bonferroni multiple comparisons. Error bars indicate 95% CI. ANOVA, analysis of variance.