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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: J Thromb Haemost. 2022 Dec 22;21(3):522–533. doi: 10.1016/j.jtha.2022.10.027

Figure 7. Loss of ATXN2L increases fibrinogen protein in HepG2 cell lysates.

Figure 7.

HepG2 cells were transfected with siRNAs against FGA, FGB, FGG, or ATXN2L in the presence of IL-6. (A) ATXN2L protein was visualized by immunoblot and quantified by densitometry (upper band). (B) Fibrinogen was visualized in cell lysates by immunoblot and quantified by densitometry. All data were normalized to treatment with control siRNA (siNC), N=3–4 for each condition, bars indicate mean+standard error of the mean; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001