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The short telomere threshold for disease, which is reached only in a subset of the human population. This scheme traces telomere shortening with age in two individuals (red circles), one with a telomere length near the median at birth and one with a telomere length in the lowest decile at birth. The threshold shown is based on data from short telomere syndrome patients (as also shown in Figure 1). Telomere length nomogram adapted from Reference 6.
