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Schema showing hypothesized long and short telomere syndrome patients (red circles) with telomeres at extremes of the normal range. The melanoma phenotype in patients with long telomeres contrasts with the melanocyte loss seen in the premature graying phenotype of the short telomere syndromes, demonstrating how the short telomere aging phenotype is tumor suppressive at this extreme. Telomere length nomogram adapted from Reference 6.
