Figure 5.

Noise in cell-cycle time and cell size propagates from noise in growth parameters. (A) A colormap showing standard deviation in cell-cycle time τ (${\sigma }_{\tau }$) predicted by our stochastic simulations, as a function of intergenerational noise (${\sigma }_K,{\sigma }_{\mathrm{\Lambda }}$) and intragenerational noise (${\sigma }_{\nu k}$). Each axis is normalized by dividing the varied parameter(s) by the standard value(s) fitted to the data, and the scale of ${\sigma }_{\tau }$ is likewise normalized by the unperturbed value. Each parameter is varied $\pm 50\%$ along each axis. Bins sample 5000 generations for a single cell. (B) A colormap showing normalized standard deviation in initial cell size (${\sigma }_{L_0}/{\sigma }_{L_0}^{\text{fitted}}$), predicted by our simulations, as a function of intergenerational and intragenerational noise. To see this figure in color, go online.