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. 2023 Feb 27;12(5):e026696. doi: 10.1161/JAHA.122.026696

Table 4.

Adjusted Associations of Duration of Any Breastfeeding With DBP, MAP, LDL‐C, and Glucose Stratified by Presence of HDP

<1 month 1 to <3 months 3 to <6 months 6 to <9 months 9+ months
Mean difference (95% CI) Mean difference (95% CI) Mean difference (95% CI) Mean difference (95% CI) Mean difference (95% CI)
No HDP
DBP, mm Hg −0.21 (−1.74 to 1.32) −1.30 (−2.72 to 0.12) −0.02 (−1.31 to 1.26) −0.28 (−1.59 to 1.03) −1.18 (−2.40 to 0.05)
MAP −0.13 (−1.60 to 1.33) −1.19 (−2.56 to 0.17) 0.25 (−0.97 to 1.48) −0.07 (−1.33 to 1.19) −0.95 (−2.12 to 0.23)
LDL‐C, mmol/L 0.03 (−0.10 to 0.16) 0.01 (−0.11 to 0.13) 0.01 (−0.10 to 0.12) −0.05 (−0.16 to 0.06) −0.05 (−0.15 to 0.05)
Glucose, % change −0.27 (−1.92 to 1.38) −0.77 (−2.36 to 0.82) 0.84 (−0.54 to 2.21) −0.66 (−2.05 to 0.73) −0.15 (−1.44 to 1.13)
HDP
DBP, mm Hg −3.25 (−6.85 to 0.34) −3.08 (−6.17 to 0.02) −2.67 (−5.76 to 0.41) −4.87 (−7.87 to −1.88)* −1.67 (−4.59 to 1.24)
MAP −2.93 (−6.33 to 0.47) −3.11 (−6.04 to −0.17)* −2.87 (−5.79 to 0.04) −4.61 (−7.45 to −1.77)* −1.95 (−4.71 to 0.81)
LDL‐C, mmol/L −0.26 (−0.53 to 0.02) −0.41 (−0.66 to −0.17) −0.22 (−0.45 to 0.02) −0.40 (−0.62 to −0.17) −0.27 (−0.50 to −0.04)*
Glucose, % change −1.18 (−5.97 to 3.61) −4.78 (−8.98 to −0.59)* −1.91 (−6.18 to 2.36) −3.98 (−8.05 to 0.09) −2.96 (−6.95 to 1.02)

Reference group=participants who never breastfed. All outcomes were adjusted for age at delivery, race, prepregnancy body mass index, parity, smoking, marital status, manual occupational social class, university education, and gestational diabetes. Blood pressure outcomes were further adjusted for use of antihypertensive medications. Glucose, insulin, and proinsulin outcomes were further adjusted for diabetes medications. Low‐density lipoprotein cholesterol (LDL‐C) outcomes were further adjusted for cholesterol‐lowering medications. DBP indicates diastolic blood pressure; HDP, hypertensive disorders of pregnancy; and MAP, mean arterial pressure.

*

P<0.05.

P<0.001 (Bonferroni correction).