Table 1.
Population Characteristics and Dispensing of Antihypertensive Drugs
| Total, N=2 822 616 | Chronic hypertension before pregnancy | |||||
|---|---|---|---|---|---|---|
| No, n=2 780 267 | Yes, n=42 349 | |||||
| No. or mean | Percentage or SD | No. or mean | Percentage or SD | No. or mean | Percentage or SD | |
| Maternal characteristic | ||||||
| Maternal age, y | 28.29 | (5.38) | 28.29 | (5.36) | 28.29 | (6.01) |
| Multiple pregnancy | 56 544 | 2.00 | 55 210 | 1.99 | 1334 | 3.15 |
| Smoking | 251 303 | 8.90 | 246 635 | 8.87 | 4668 | 11.02 |
| Social deprivation | 389 005 | 13.78 | 382 864 | 13.77 | 6141 | 14.50 |
| Medical history | ||||||
| Obesity | 116 556 | 4.13 | 110 410 | 3.97 | 6146 | 14.51 |
| Diabetes | 14 510 | 0.51 | 12 783 | 0.46 | 1727 | 4.08 |
| Previous veinous thromboembolism | 3491 | 0.12 | 3321 | 0.12 | 170 | 0.40 |
| Antihypertensive drugs dispensing before 20 wks of gestation* | ||||||
| ACE inhibitors/AIIRA | … | … | … | … | 8078 | 19.07 |
| β‐blockers | … | … | … | … | 22 171 | 52.35 |
| Diuretics | … | … | … | … | 3696 | 8.73 |
| Calcium channel blockers | … | … | … | … | 8194 | 19.35 |
| Other | … | … | … | … | 5908 | 13.95 |
| None | … | … | … | … | 33 463 | 79.02 |
SD data are shown in parentheses. ACE indicates angiotensin‐converting enzyme; and AIIRA, angiotensin II receptor antagonist.
*
Number of women diagnosed with chronic hypertension before pregnancy with at least 1 dispensing of antihypertensive drugs between 1 year before the date of pregnancy and 20 weeks of amenorrhea.