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. 2023 Feb 27;12(5):e027266. doi: 10.1161/JAHA.122.027266

Table 2.

Numbers and Proportions of Infant and Maternal Adverse Events, According to Hypertension Status

No hypertension, n=2 780 267 Chronic hypertension, n=42 349 Chronic hypertension treated during pregnancy, n=22 816 Chronic hypertension untreated during pregnancy, n=19 533 Chronic hypertension vs no hypertension, P value Treated hypertension vs untreated hypertension, P value
No. Percentage No. Percentage No. Percentage No. Percentage
Infant events
Infant death 12 136 0.44 355 0.84 201 0.88 154 0.79 <0.0001 0.2977
Small‐for‐gestational age* 220 449 13.96 5203 24.38 3223 28.77 1980 19.54 <0.0001 <0.0001
Premature delivery threat 277 722 9.99 5514 13.02 3288 14.41 2226 11.40 <0.0001 <0.0001
Preterm birth 201 767 7.30 8010 19.11 4857 21.52 3153 16.30 <0.0001 <0.0001
Preterm birth stages <0.0001 <0.0001
Moderate preterm (≥32 WG) 170 722 6.17 6093 14.54 3682 16.32 2411 12.47
Very preterm (27–31 WG) 24 271 0.88 1569 3.74 983 4.36 586 3.03
Extremely preterm (<27 WG) 6774 0.24 348 0.83 192 0.85 156 0.81
Maternal events
Gestational diabetes 229 593 8.26 7110 16.79 4547 19.93 2563 13.12 <0.0001 <0.0001
Preeclampsia 75 222 2.71 7237 17.09 4124 18.08 3113 15.94 <0.0001 <0.0001
Cesarean delivery 736 920 26.51 20 864 49.27 12610 55.27 8254 42.26 <0.0001 <0.0001
Obstetric hemorrhage 158 957 5.72 2982 7.04 1582 6.93 1400 7.17 <0.0001 0.35
Venous thromboembolism 3281 0.12 121 0.29 62 0.27 59 0.30 <0.0001 0.56
ACS or stroke 770 0.03 45 0.11 16 0.07 29 0.15 <0.0001 0.01
Death postpartum 152 0.01 13 0.03 9 0.04 4 0.02 <0.0001 0.27

ACS indicates acute coronary syndrome; and WG, weeks of gestation.

*

Birth weight was available from 2013; percentages for small for gestational age are calculated for available data for the period from 2013 to 2018.

Preterm percentages are calculated for live births.