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. 2023 Feb 27;12(5):e027266. doi: 10.1161/JAHA.122.027266

Table 3.

Number and Type of Antihypertensive Drugs Dispensed to Women With Chronic Hypertension Treated During Pregnancy at All 3 Trimesters of the Pregnancy and Postpartum

Indication* 1 year before pregnancy First trimester Second trimester Third trimester Postpartum
No. Percentage No. Percentage No. Percentage No. Percentage No. Percentage
Contraindicated drug 4563 31.7 1498 10.9 328 2.0 105 0.7 1584 12.8
Nonindicated drug 8684 60.3 7144 51.8 7022 42.6 5013 33.9 4382 35.3
Indicated drug 1143 7.9 5153 37.4 9123 55.4 9661 65.4 6436 51.9
All drugs 14 390 100 13 795 100 16 473 100 14 779 100 12 402 100
*

Angiotensin‐converting enzyme inhibitors, angiotensin II receptor antagonists, and aliskiren were considered contraindicated drugs during pregnancy (formally contraindicated in the second and third trimesters). Methyldopa, nicardipine, labetalol, and nifedipine were considered indicated drugs during pregnancy. All other molecules were considered nonindicated during pregnancy.