Table 3.
Indication* | 1 year before pregnancy | First trimester | Second trimester | Third trimester | Postpartum | |||||
---|---|---|---|---|---|---|---|---|---|---|
No. | Percentage | No. | Percentage | No. | Percentage | No. | Percentage | No. | Percentage | |
Contraindicated drug | 4563 | 31.7 | 1498 | 10.9 | 328 | 2.0 | 105 | 0.7 | 1584 | 12.8 |
Nonindicated drug | 8684 | 60.3 | 7144 | 51.8 | 7022 | 42.6 | 5013 | 33.9 | 4382 | 35.3 |
Indicated drug | 1143 | 7.9 | 5153 | 37.4 | 9123 | 55.4 | 9661 | 65.4 | 6436 | 51.9 |
All drugs | 14 390 | 100 | 13 795 | 100 | 16 473 | 100 | 14 779 | 100 | 12 402 | 100 |
Angiotensin‐converting enzyme inhibitors, angiotensin II receptor antagonists, and aliskiren were considered contraindicated drugs during pregnancy (formally contraindicated in the second and third trimesters). Methyldopa, nicardipine, labetalol, and nifedipine were considered indicated drugs during pregnancy. All other molecules were considered nonindicated during pregnancy.