Table 1.
Main Characteristics of Study Participants According to the Presence and Severity of Peripheral Artery Disease
| Total | PAD | No PAD | P | ||
|---|---|---|---|---|---|
| (n=67) | Moderate to severe (ABI <0.60; n=15) | Mild (ABI 0.60–0.90; n=29) | (n=23) | ||
| Characteristic | |||||
| Age, y | 65.0 (6.8) | 64.9 (7.8) | 65.4 (6.6) | 64.6 (6.6) | 0.903 |
| Sex, female | 16 (23.9%) | 3 (20.0%) | 7 (24.1%) | 6 (26.1%) | 0.911 |
| Race, Black | 48 (71.6%) | 10 (66.7%) | 23 (79.3%) | 15 (65.2%) | 0.475 |
| Current or former smoking | 59 (88.1%) | 15 (100.0%) | 28 (96.6%) | 16 (69.6%) | 0.004 |
| Body mass index, kg/m2 | 28.2 (5.4) | 28.6 (4.6) | 28.1 (5.7) | 28.2 (5.8) | 0.951 |
| ABI | 0.83 (0.26) | 0.50 (0.08) | 0.74 (0.08) | 1.14 (0.08) | <0.001 |
| Comorbidities | |||||
| Myocardial infarction | 8 (12.1%) | 2 (13.3%) | 4 (13.8%) | 2 (9.1%)† | 0.897 |
| Angina | 6 (9.1%) | 2 (13.3%) | 3 (10.3%) | 1 (4.5%)† | 0.649 |
| Congestive heart failure | 5 (7.6%) | 0 (0.0%) | 4 (13.8%) | 1 (4.5%)† | 0.285 |
| Cancer | 9 (13.4%) | 4 (26.7%) | 3 (10.3%) | 2 (8.7%) | 0.306 |
| Chronic obstructive pulmonary disease | 12 (17.9%) | 3 (20.0%) | 5 (17.2%) | 4 (17.4%) | 1.000 |
| Physical performance | |||||
| 6‐minute walk distance, m | 367.0 (122.5) | 302.7 (95.2) | 366.4 (96.3) | 409.8 (150.9) | 0.029 |
| 4‐m gait speed at usual pace, m/s | 0.85 (0.22) | 0.85 (0.17) | 0.85 (0.19)* | 0.84 (0.28) | 0.959 |
| 4‐m gait speed at fast pace, m/s | 1.19 (0.32) | 1.20 (0.22) | 1.21 (0.28)* | 1.15 (0.41) | 0.774 |
| Short physical performance battery summary score | 9.8 (2.5) | 10.7 (1.6) | 9.7 (2.3)* | 9.2 (3.1)† | 0.222 |
Data are mean (SD) or n (%). ABI indicates ankle‐brachial index; and PAD, peripheral artery disease.
*
n=28.
†
n=22.